16th January. Sequel to "Love & Other Drugs"

Maggie's condition has deteriorated to the point where she no longer enjoys sex. When she has lost most of her personality and keeps shitting herself Jamie decides to smother her with a pillow. He then meets another, younger, woman with a keen interest in sex but this time with a psychiatric illness. She ends up cutting his penis off in the middle of the night. Jamie is then forced to reinvent himself as the transsexual escort "jamie Lee".